San Francisco generally recovers from early season slumps. Geno Smith generally loses to the Niners — he’s 0-3 against them all-time with a passer rating more than 10 points lower against his divisional rival than his Seattle average. The Bears’ defense is absolutely legit and this rookie QB they’ve got might not be too bad, either!

Drake Maye will get the start for the lowly Patriots, but did you know rookie quarterbacks have covered AND WON seven straight starts? Also, 7+ point underdogs are an incredible 7

Chris "The Bear" Fallica delivers his best bets for NFL Week 6. Check out his latest picks, including why he's wagering on the Bengals to cover on the road.

Joining me for 2024 is a six-person panel ranging from FTW editors (Charles Curtis, Mary Clarke) to betting analysts (Prince Grimes) to NFL writers (Robert Zeglinski, Andrew Joseph, Meghan Hall). Here are our Week 6 picks:

SportsLine AI evaluated the Week 6 NFL odds and revealed its NFL predictions, NFL score predictions, and NFL betting picks for every game

Which NFL teams have the best chances of winning their games on the NFL Week 6 schedule? ESPN Analytics has revealed its Matchup Predictor numbers for the 14 games in the league this week, and they offer some interesting win probabilities.

B o Nix and the Denver Broncos have won three consecutive games and will host the Los Angeles Chargers for an AFC West rivalry in Week 6. The Broncos have won five consecutive hom

From the NFC South last week, we move to the NFC West to kick off the NFL Week 6 calendar as the San Francisco 49ers and Seattle Seahawks both look to stave off a two-game losing streak after suffering upsets in Week 5 to the Arizona Cardinals and New York Giants,