Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

BACKGROUND: In the phase 3 randomized controlled study ATTRibute-CM (Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy), acoramidis, a transthyretin stabilizer, ...

A cardiac catheterization takes ≈45 minutes to complete. After a coronary angiogram, depending on the severity and pattern of any blockages detected in the coronary arteries, 3 common treatment paths ...

Considering that IE is a relatively rare disease, ongoing updates to clinical data and patient backgrounds are essential for providing precision diagnoses and effective treatments. This study uses a ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a high incidence of indeterminate left ventricular (LV) filling pressure. We ...

Left ventricular (LV) systolic function is a powerful prognosticator of clinical outcome following percutaneous coronary intervention (PCI), 1, 2, 3 and patients who do not have in‐hospital LV ...

Heart failure with preserved ejection fraction (HFpEF) is a growing health care concern due to its increasing incidence, high morbidity and mortality, and lack of effective treatment options. 1, 2, 3 ...

Since it was first defined by the American Heart Association in 2010, cardiovascular health (CVH) has been extensively studied across the life course. In this review, we present the current literature ...

In the United States, SCD is recognized as a leading cause of death. However, its relative public health burden, especially in younger Americans, remains less clear. 4 Previous investigations ...

BACKGROUND: Poststroke depression (PSD) affects ≈33% of individuals 1 year after a stroke. Blood-brain barrier (BBB) dysfunction in the nucleus accumbens (NAc), a hub for emotional processing, reward, ...

A total of 8 canines, with a weight of 35 to 40 kg and an age of 2.90±0.56 years, were randomized after the surgical procedure by the weight order into 2 observation groups: a 48-hour group (N=4) and ...

Bicuspid aortic valve (BAV) and thoracic aortic aneurysms (TAAs) leading to aortic dissections, called thoracic aortic disease (TAD), are highly heritable and cause a significant cumulative burden of ...