In the phase 3 randomized controlled study ATTRibute-CM (Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy), acoramidis, a transthyretin stabilizer, demonstrated ...

Thrombocytopenia is defined as a platelet count below the lower limit of the normal range used by the laboratory performing the count. Typically, the threshold is set at 150×10 9 /L or 100×10 9 /L 3 ...

Considering that IE is a relatively rare disease, ongoing updates to clinical data and patient backgrounds are essential for providing precision diagnoses and effective treatments. This study uses a ...

From 90 days from the start of closeout to the end of double-blind treatment, the annualized risk of cardiovascular death or hospitalization for heart failure was lower in empagliflozin-treated ...

Heart failure (HF) is associated with poor outcomes in people with chronic kidney disease, yet it is unknown whether outcomes differ by HF subtype. This study aimed to examine associations of incident ...

Heart failure (HF) is responsible for substantial morbidity among the estimated 6 million affected adults in the United States. 1 For HF with reduced ejection fraction (HFrEF), optimal ...

Within 72 hours of admission, cTnT, cTnI, and CK were increased compared with upper reference limits (URLs) in 56 of 57 (98%), 37 of 42 ( [88%] P =0.03 versus cTnT), and 43 of 57 ( [75%] P <0.001 ...

In their 2020 report, the European Environment Agency highlighted that many people remain exposed to high road traffic noise levels. 10 The European Environment Agency estimated that at least 20% of ...

Left ventricular (LV) systolic function is a powerful prognosticator of clinical outcome following percutaneous coronary intervention (PCI), 1, 2, 3 and patients who do not have in‐hospital LV ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a high incidence of indeterminate left ventricular (LV) filling pressure. We ...

One of the most important sectors of health care is the ability to access not only quality health care services but diversity for comprehensive health care delivery. Not all children with congenital ...

Guideline-directed medical therapies and guideline-directed nonpharmacological therapies improve quality of life and survival in patients with heart failure (HF), but eligible patients, particularly ...