Main text Please take note of the following when preparing your manuscript for PNAS: Do not include statements of novelty or priority. Avoid laboratory jargon. Use correct chemical names. Specify ...

We thank Jun Chen for providing wdr5 mutant, Anming Meng for providing rnaseh1 MO, Dengli Hong for providing 2×HBD, and Yu Sun for assistance during the experimental process. This work was supported ...

The Earth’s rotation has been decelerating throughout its history due to tidal dissipation, but the variation of the rate of this deceleration through time has not been established. We present a ...

Many cities seek to alleviate extreme heat via planting trees. However, the cooling achieved by such programs is debated because previous analyses address scales much smaller than the whole-city scale ...

Sleep need accumulates during waking and dissipates during sleep to maintain sleep homeostasis (process S). Besides the regulation of daily (baseline) sleep amount, homeostatic sleep regulation ...

The discovery and engineering of herbicide-resistant genes represent a critical frontier in modern crop breeding. Here, we focused on unraveling the intricate mechanisms underlying herbicide ...

This study establishes a causal link between information and communication technology (ICT) usage and workforce geographical diversity, offering insights into how technology shapes labor mobility and ...

Mitochondrial Ca 2+ uptake has long been recognized in the positive regulation of oxidative metabolism in a spectrum of cells and tissues (1, 2). In the heart, it has been shown to support homeostatic ...

The expansion of marine protected areas (MPAs) is a crucial part of global conservation efforts (1). The “30x30” initiative, for example, aims to protect at least 30% of the world’s oceans by 2030 ...

Water molecules at the solid–liquid interface display intricate behaviors sensitive to small changes. The presence of different interfacial components, such as cations or functional groups, shapes the ...

When analyzing artworks, discerning the visual clarity of compositions is pivotal. Inspired by the perceptual tactics of digital artists, we introduce a metric for quantifying clarity through a unique ...

The deterioration of the world’s ecosystems has led to numerous calls for effective and scalable conservation solutions [e.g., (1, 2)]. While conservation can include a broad range of actions, the ...