SMA is a motor neuron disease characterised by generalised muscle atrophy and weakness. It is caused by the dysfunction and eventual death of motor neurons, due to deletions of SMN1 in 95% of patients ...

Background and Objectives Prolonged neonatal jaundice is defined as jaundice persisting in a term neonate at 14 days and a preterm neonate at 21 days of age. Prolonged neonatal jaundice is most ...

Aims • Raise awareness of plastic pollution and its dangers to marine animals and potentially humans. • Education of children in schools • Litter-picking Methods In 2017 WASUP was founded. A working ...

Background Mental health problems are prevalent in children and young people (CYP). Children with neurodevelopmental disorders such as ASD have co-morbid mental health difficulties which add to the ...

Objectives Asthma is the most common chronic condition in children, affecting 2–3 in every primary school class.1 Asthma disproportionately affects children living in poverty due to air pollution, ...

Introduction More than half of all drugs are still prescribed off-label to children. To support off-label dosing, pharmacokinetic (PK) data are needed. Physiologically-based pharmacokinetic (PBPK) ...

Objectives Hand dominance usually develops in children around 18 months old, while earlier hand preference may indicate cerebral palsy.1 Hand preference in humans is thought to be related to the ...

Methods We used novel linkage between health and education records from the Education and Child Health Insights from Linked Data (ECHILD) database to develop a whole-country cohort of children ...

Objectives Newborn screening helps to identify inherited disorders at their asymptomatic stage and intervene before babies go into the symptomatic phase. A number of Inherited Metabolic Disorders ...

Aims The HEADSSS assessment is an internationally used tool to help give structure and framework to an assessment of an adolescent patient. Objective To analyze the knowledge among doctors in the ...

Methods Our aim in this observational study was to assess safety of the delivery room cuddles for babies born < 32 weeks’ gestation. As part of the stabilisation for babies born < 32 weeks, if certain ...

Background The use of biologic agents allows the application of precision medicine in the treatment of paediatric severe asthma. Aim To describe the real-life effectiveness of biologic agents in ...