Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Prostate cancer (PCa) is the second most frequently occurring cancer and the fifth leading cause of cancer mortality among men worldwide in 2022 (Bray et al, 2024).Androgen receptor (AR) is considered ...

EMBO Press publishes five scientific journals: The EMBO Journal - Submit here The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology ...

Rheumatoid arthritis (RA) is associated with heart and lung dysfunction. Current therapies fail to attenuate such complications. Here, we identify formyl-peptide receptor type 2 (FPR2) as a ...

Fungal infections and autoimmunity share a complex, bidirectional relationship that significantly impacts patient outcomes. Emerging evidence highlights how fungal pathogens contribute to autoimmune ...

Neural stem cells (NSCs) in the mammalian brain decline rapidly with age, leading to impairment of hippocampal memory function in later life. However, the relationship between epigenetic remodeling ...

Chloride (Cl −) ions cause major damage to crops in saline soils.Understanding the key factors that influence Cl − uptake and translocation will aid the breeding of more salt-tolerant crops. Here, ...

We demonstrate that TP53 deficiency in AML cells confers resistance to CAR T-cell therapy by inducing CAR T-cell dysfunction. We propose a model in which difficult-to-kill TP53-mutant AML cells ...

To attribute disease to cell type, and molecular features of cells to disease state, we need to define and distinguish cell types, subtypes and states (Dann et al, 2023).We follow others (Fleck et al, ...

The bacterial homolog DgoT (from E. coli) transports negatively charged galactonate in symport with more than one proton and, thus, differs from mammalian SLC17s in both its main substrate and ...

De novo protein design is of fundamental interest to synthetic biology, with a plethora of computational methods of various degrees of generality developed in recent years. Here, we introduce ...