Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

MCM8 deficiency impairs meiotic homologous recombination repair, but the specific role of MCM8 in mitotic germ cells remains poorly understood. This study reveals that MCM8 interacts with helicase ...

Cells rapidly remodel their proteomes to align their cellular metabolism to environmental conditions. Ubiquitin E3 ligases enable this response, by facilitating rapid and reversible changes to protein ...

Arthritis was induced in mice exposed to high blood levels of homocysteine. Hyper-homocysteinemia arthritic animals develop diastolic dysfunction (the left ventricle does not dilate properly) with ...

Neural stem cell (NSC) function in mammalian brains declines during aging, but the molecular mechanisms involved remain ill-defined. Here, integrated multi-omics reveals continuous alterations of ...

Motile cells can use and switch between different modes of migration. Here, we use traction force microscopy and fluorescent labeling of actin and myosin to quantify and correlate traction force ...

We report apelin-specific cleavage and activation by Furin as a key player in colon cancer and early events of colon cancer and liver cells interaction leading to metastasis. Alteration of apelin ...

Correction to: EMBO Molecular Medicine (2024) 16:294–318. https://doi.org/10.1038/s44321-024-00025-1 | Published online 31 January 2024 ...

Recent evidence has revealed that small polypeptides (containing fewer than 100 amino acids) can be translated from noncoding RNAs (ncRNAs), which are usually defined as RNA molecules that do not ...

The microbiome plays an important role in shaping plant growth and immunity, but few plant genes and pathways impacting plant microbiome composition have been reported. In Arabidopsis thaliana, the ...

Rare tumor has a huge unmet medical need without standard regimens, calling for novel therapeutic interventions. The National Cancer Center of China identified a threshold of incidence for rare tumor ...